AMBOSS was founded by doctors, for doctors, in 2012. A group of young residents became frustrated by the limitations of the medical education system: the multitude of disconnected resources available led  to more time spent researching topics than mastering them. They took matters into their own hands and together completely reshaped the path to becoming a physician. They created AMBOSS, a digital medical resource that could single-handedly support students in the classroom as well as later on as a clinical companion.

In a few short years, leading doctors from Harvard, Yale, and Stanford joined the AMBOSS team and focused their efforts on developing materials specific to the USMLE® Step and NBME® Shelf exams, and a successful US launch in 2017 coincided with headquarters opening in New York.  Since then, AMBOSS has grown from a small team to over 300 highly trained physicians, scientists, and software engineers. Together, they leverage technology to provide accurate, while accessible, medical knowledge to physicians around the world.

Today, more than a million healthcare professionals in over 180 countries rely on AMBOSS. Over 50 medical schools around the world, including the New York University School of Medicine (NYU) and Yale University, have adopted it as an essential study resource. In addition, Helios, the largest hospital group in Europe, rolled out AMBOSS as the foundational medical reference for its doctors.